HAPPY WEDNESDAY TO THE STREET.
The Meme ETF is back — just in time to test whether we’ve learned anything since 2021.
Roundhill’s MEME fund relaunched today with a fresh crop of volatile darlings like Opendoor $OPEN ( ▼ 3.18% ), Plug Power $PLUG ( ▲ 0.27% ), and QuantumScape $QS ( ▲ 5.02% ).
Last time it debuted, the Nasdaq topped out within weeks.
🟨 | US stocks were mixed today. The S&P and Nasdaq rose to records, but the DJIA wavered, as the market digested the latest Fed minutes.
📈 | One Notable Gainer: AST SpaceMobile $ASTS ( ▲ 6.69% ) jumped after announcing a deal with Verizon $VZ ( ▼ 0.9% ) to deliver satellite-based cell service.
📉 | One Notable Decliner: Fair Isaac $FICO ( ▲ 1.97% ) fell after Equifax $EFX ( ▼ 1.98% ) challenged FICO’s dominance in mortgage credit scoring.
Finally, read to the end for the entire investor psyche in a single meme…
— Brooks & Cas
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STOCK HEATMAPS

S&P 500 Heatmap. Credit: Finviz

All Stock Heatmap. Credit: Finviz

Global ADR snapshot. Credit: Finviz
Market Movers
ROCKET LAB, COREWEAVE, JOBY
$RKLB ( ▲ 3.89% ) Rocket Lab's Shares Lift on New Multi-Mission Satellite Launch Deals (Investopedia)
$CRWV ( ▼ 0.87% ) CoreWeave stock rallies as company introduces new AI tools for developers (CNBC)
$JOBY ( ▼ 1.7% ) Joby Tumbles On $513 Million Stock Offering After Air Taxi Demos (IBD)
$VSAT ( ▼ 2.02% ) Viasat secures contract for U.S. Space Force satellite program (Investing.com)
$CFLT ( ▲ 2.58% ) Data streaming software maker Confluent explores sale, sources say (Reuters)
OVERHEARD ON THE STREET
CNBC: Fed minutes showed officials favored rate cuts this year, with most expecting two more as labor market weakness persisted.
Bloomberg: Elon Musk’s xAI expanded its funding round to $20B with backing from Nvidia $NVDA ( ▲ 2.76% ), using a special vehicle to finance Colossus 2.
CNN: Domino’s $DPZ ( ▼ 0.6% ) unveiled its first rebrand in 13 years with a bolder logo, new uniforms, and a Shaboozey-performed jingle.
QZ: KFC $YUM ( ▼ 0.58% ) brought back its Original Honey BBQ chicken and cut sandwich prices to $3.99 as nostalgia-driven menu revivals boost sales.
Reuters: GM $GM ( ▼ 0.12% ) scrapped its plan to extend $7,500 EV lease tax credits past September after the federal subsidy expired.
Tomorrow's Trade Idea, Today
A SMALL-CAP WITH BIG AMBITION

Big Bet on a Small Biotech
Guggenheim $GOF ( ▼ 0.17% ) says shares of CG Oncology $CGON ( ▲ 6.73% ) could more than double from here. The only question left for investors is, “Who…?”
The firm initiated coverage of the little-known bladder cancer treatment biotech with a Buy rating and a $90 price target, implying around 121% upside from the stock’s close today. Analyst Brad Canino highlighted CG Oncology’s strong footing in a growing segment with substantial pricing power and long treatment durations.
He described the company’s lead therapy, cretostimogene, as “best-in-class” in efficacy, durability, and safety, noting that it will enter FDA review next year.
A Promising Cancer Candidate
Cretostimogene is an oncolytic immunotherapy designed to stimulate the immune system to target bladder cancer cells. Canino said the treatment’s profile is particularly well-suited to non-muscle invasive bladder cancer (NMIBC) patients, who seek to avoid invasive surgeries such as cystectomy.
Equally important, Canino noted, is that NMIBC patients tend to have a non-lethal form of cancer, heightening the demand for drugs with pristine safety records — an area where cretostimogene could potentially stand out.
Guggenheim believes that the combination could help CG Oncology carve out a leading position in a field that has seen limited innovation over the past decade.
Catalysts on the Horizon
Guggenheim also pointed to what it called a “potentially attractive catalyst path,” citing a string of data releases and regulatory updates expected over the next two years. Those milestones could help maintain investor attention on the name as it moves closer to commercialization.
Wall Street appears to agree: all 12 analysts covering CG Oncology currently rate it a Buy or Strong Buy, according to LSEG data.
For investors willing to stomach biotech volatility, analysts say the company’s mix of strong science, a clear market opportunity, and multiple near-term catalysts could make it one of the most compelling small-cap healthcare stories heading into 2026.
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ON OUR RADAR
QZ: Flight delays and cancellations mounted as unpaid air traffic controllers called in sick during the second week of the US government shutdown.
CNBC: What’s more, the FAA warned flight delays could worsen amid the shutdown due to an air traffic controller shortage already disrupting major airports.
Axios: Retailers and drone firms criticized a proposed FAA rule requiring TSA-style screening for delivery staff, warning it would cripple drone operations.
AP: IMF chief Kristalina Georgieva said global growth should hold at 3% despite Trump’s tariffs but warned that uncertainty is “the new normal”.
CNN: Denmark announced plans to ban social media for children under 15, citing rising youth anxiety and declining social interaction.
STREET TWEET
Me standing in the shower wondering if I should sell my entire stock portfolio and rotate it all into gold and bitcoin
— #Ramp Capital (#@RampCapitalLLC)
1:25 PM • Oct 8, 2025
Weathering the liquidity storm.
It’s been that kind of week: bond yields up, stocks sideways, and the internet once again debating whether gold and Bitcoin are “real” hedges.
Through it all, our amphibious friend remains unmoved.
TUESDAY POLL RESULTS
Are you bullish or bearish on Astera Labs $ALAB ( ▲ 1.66% ) over the next 12 months?
▇▇▇▇▇▇ 🐂 Bullish
▇▇▇▇▇▇ 🐻 Bearish
And, in response, you said:
🐂 Bullish — “If nothing else, the coattails effect will support the price.”